I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. Docetaxel users have reported severely itchy rashes on the feet, hands, arms, face and chest. Our team includes experienced medical writers, award-winning journalists, researchers and certified medical and legal experts. Taxotere is a strong chemotherapy drug that doctors prescribe to treat certain types of cancer. Retrieved from, U.S. Food and Drug Administration. It has had a traumatic toll on my relationship with my husband, my self-image, my self-esteem, and it has been hard on my kids, too.. After first AC on Wed. and doing "okay" Thurs. Signs of serious complications include severe diarrhea and abdominal pain. It can be anywhere from the 50s to off days. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go Please assign a menu to the primary menu location under MENU. Has anyone moved to access better cancer care? I wish I rang sooner. In a 2017 study by Summer Karafiath and colleagues, three out of 21 women developed docetaxel-induced neuropathy versus 15 out of 21 women in the paclitaxel group. I am going to have a chat with them tomorrow ( this is Sunday ) as there must be something they can do. So I feel that is a positive thought. Testing Positive for COVID-19: It Felt Like I Had a Compression Belt Around My Chest, COVID-19: A Consumers Guide to the Coronavirus, Trial Attorney and Pharmaceutical Litigation Expert, FDA Gives Baby Formula Manufacturers New Guidance, Erika Sward of American Lung Association Reveals the Dangers of Vaping and IQOS, Breast Cancer Survivor Files Permanent Hair Loss Lawsuit, Breast Cancer Survivor who took Taxotere: I Should Not be Permanently Disfigured, This article contains incorrect information, This article doesn't have the information I'm looking for, Toxic death, low blood cell counts, liver toxicity, fluid retention, hypersensitivity reactions, Blood disorders (low blood cell count, anemia), hair loss, fluid retention, nausea, vomiting, fatigue, excessive tearing (epiphora), Take antihistamines and corticosteroids before therapy, lower medication dose, discontinue medication, Causes harm to unborn babies; breastfeeding not recommended, EzriCare & Delsam Artificial Tears Lawsuits, Presentation and Management of Docetaxel-related Adverse Effects in Patients with Breast Cancer, https://www.mdpi.com/2227-9717/9/7/1086/htm, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=45e6dce4-92e2-4ad1-bf11-bbcefb753636&audience=consumer#S6.1, https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020449s079lbl.pdf, https://n.neurology.org/content/88/16_Supplement/P6.172, https://www.telegraph.co.uk/lifestyle/wellbeing/healthadvice/11841436/I-survived-cancer-but-drugs-left-me-with-permanent-alopecia.html, http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Docetaxel_monograph.pdf, https://www.sciencedirect.com/science/article/pii/S0959804914011496, https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-warns-cancer-drug-docetaxel-may-cause-symptoms-alcohol, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041377/, https://abstracts.ncri.org.uk/abstract/long-term-hair-loss-in-patients-with-early-breast-cancer-receiving-docetaxel-chemotherapy-3/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769512/, https://pubmed.ncbi.nlm.nih.gov/22571858/, https://webeye.ophth.uiowa.edu/eyeforum/cases/31-dacryostenosis.htm, https://www.ncbi.nlm.nih.gov/pubmed/16110015/, https://jamanetwork.com/journals/jamaophthalmology/fullarticle/268866, https://www.ncbi.nlm.nih.gov/pubmed/9205828. Those who receive TAC need to be monitored for delayed myelodysplasia or myeloid leukemia. How many treatments is she having? About 12% of patients who had received 100 mg/m2 of Taxotere during clinical studies experienced febrile neutropenia. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. According to the medication insert, women who had taken corticosteroids before their infusions did not suffer severe skin rashes. Thanks again for all the useful tips, it's good to share problems, you dont feel so alone, hope you are very well! I was on taxotere and idI was on taxotere and id have my treatments on monday, and wednesday & thursdays were my bad days. Typically, hair grows back within three to six months after discontinuation of treatment. Independent studies in clinical practice found higher numbers. But, according to the medication label, the chemotherapy drug has a few common side effects. The agency revised the drugs label to include warnings about the risk. WebAnswer (1 of 12): I lived in the LA area all my life64 years. If you are a Mayo Clinic patient, this could I'm fortunate in that my husband is self employed. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? How to Spy on someones Computer? Statistically speaking, the worst day of the week to travel by car is Saturday, which is great news if you dont work weekends. My lovely Onco took no persuading, as I expected she had already made the decision. The information on Drugwatch.com has been medically and legally reviewed by more than 30 expert contributors, including doctors, pharmacists, lawyers, patient advocates and other health care professionals. health information, we will treat all of that information as protected health Make a list of your medications. Advertising revenue supports our not-for-profit mission. Some studies also link the drug to permanent hair loss on the scalp and the rest of the body, including eyebrows and eyelashes. the unsubscribe link in the e-mail. It is also used together with other medicines (eg, cyclophosphamide, doxorubicin) to treat node-positive breast cancer that can be removed by surgery. Retrieved from, Thorp, N. et al. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals. Drugwatch.com has provided reliable, trusted information about medications, medical devices and general health since 2008. Click here for an email preview. Taxol/Taxotere and Cytoxan (TC) therapy is one of the most common types of chemotherapy given to women with early-stage breast cancer. information and will only use or disclose that information as set forth in our notice of Its normal to feel completely wiped out when you begin this medication. WebWorst Week is an American sitcom television series that premiered on CBS on September 22, 2008. These are some of the most common or important side effects: Allergic reactions are possible with this medication. I was initially told to have the chemo in the hope they could conserve the breast! Taxotere, also known as docetaxel, is a chemotherapy drug that doctors prescribe to treat several different cancers most commonly, breast cancer. Medications will be given before each treatment to decrease the risk of this Avoid large crowds and people who are sick (i.e. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may be used. Of the four drugs injected into my system every 21 days, Taxotere from European yews (or Taxol from Pacific yews) is most common. It really helped me that there was a gap between the two sets of chemo cycles, gave me a chance to recover a bit from the taxotere before starting the treatments again. An absolutely horrid drug. This can cause gastrointestinal perforation and dehydration. Painkillers, she had all the same things as you. There are several things you can do to prevent or relieve constipation. Keep the thoughts positive. But, some independent studies reported cases of serious skin problems in people who had been premedicated. (2017, April 17). WebWorst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. This typically begins two to three weeks after treatment starts. If the area of injection becomes red, swollen, or painful at any time during or after the injection, notify your care team immediately. Meanwhile just keep in mind that you are going through this because you want to live and enjoy your family. It's important to take things day by day. This medication contains alcohol and may cause intoxication. Severe reactions occurred in 3%-5% of patients with solid tumors and to a similar extent among metastatic breast cancer patients. After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of energy. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. Premedication reduced fluid retention with Taxotere by about 18%. The FDA advises doctors and nurses to monitor patients for signs of being drunk during and after treatment. Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin/Advil (ibuprofen), Aleve (naproxen), Celebrex (celecoxib), etc. Your web browser is no longer supported by Microsoft. Whole body ache , muscles and joints, headaches, kidney pains, swolen glands, lethargy and over emotion. It interferes with the growth of cancer cells, which are eventually destroyed by Talk to your oncology care team so they can prescribe medications to help you manage nausea and vomiting. Whole body ache , muscles and joints, headaches, kidney pains, swolen glands, lethargy and over emotion. This website and its content may be deemed attorney advertising. worst day. Studies show less than 10% of people who took docetaxel suffered the most serious symptoms, and the severity increased with the dose. Taxotere docetaxel injection, solution, concentrate. et al. Operation will be 4 weeks after my last dose. The rare side effect can have a negative impact on survivors quality of life. Synonyms for Worse days. WebJune 2009 #12. mgm42 said: DRINK WATER, DRINK WATER, DRINK WATER. Drugwatch.com partners with law firms. I went back to work on Tuesday, but wasn't feeling the greatest. This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. But they had to keep treating her with antibiotics on the off chance it was an infection. Will try the mouthwash as that is also a problem, I have a drink and seconds later my mouth is so dry again! Hi, Best wishes Jules xxx. Docetaxel injection is also used together with prednisone to treat metastatic castration-resistant prostate cancer (prostate cancer that has spread and is resistant to medical or surgical treatments that lower testosterone). Worst Days on Taxotere: 4 Side-Effects You Should Know About 1. There are several drugs designed to help ward off or treat different side effects. Grapefruit can change how your body absorbs this medication. Copyright 2000-2022 Cancer Survivors Network. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. If you notice any changes in how you feel during the infusion, let your nurse know immediately. Drugwatch is located at: Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Medications will be given before each treatment to decrease the risk of this side effect. Does anyone have any suggestions of anything that can help me .. It can be given alone or with other drugs. Docetaxel is its generic name, and it belongs to the taxane class of drugs. Youll be given steroid drugs to prevent an allergic reaction to docetaxel, which will also help reduce the chance of fluid building up. In June 2014, the U.S. Food and Drug Administration warned that docetaxel contains alcohol, which can cause patients to feel drunk after treatment. Retrieved from, Jones, S.E. Carry on being her strength and pass on my love to her xx. Skin reactions, including redness and swelling of the arms and legs with peeling of the skin, can occur with Taxotere, according to the medication label. The pathophysiological mechanism of fluid retention in advanced cancer patients treated with docetaxel, but not receiving corticosteroid comedication. In some cases, skin reactions occur just at the IV site. My poor hubby had to give them me.but they hurt and make me have achy legs.plus with the chemo sleepless nights. You will have got through it now though? Doctors typically try to give patients corticosteroids to prevent swelling, but fluid retention can still occur in some patients after premedication. After starting docetaxel, many men While receiving treatment, your WBC count can drop, putting you at a higher risk of getting an infection. She only took that a couple of times. Avoid mouthwashes that contain alcohol. Severe reactions occurred in 3%-5% of patients with solid tumors and to a similar extent among Call your healthcare provider if you do not urinate for more than 12 hours, experience shortness of breath, have an unexpected weight gain, or develop swelling in your hands, feet, ankles or legs. (1997). some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! You may also experience difficulty breathing, joint stiffness, pain, and even behavioral changes. The 3rd week I just start to feel normal.and then whoops, time for another infusion to start the cycle. This content does not have an Arabic version. (2012, May 9). Sorry for the extended message but reading these chats means I'm not alone and I'm not a hypochondriac (as believe me I've thought it) Some medicines are given by mouth as pills while others are given through an IV. Except she would always end up in hospital as her temp would spike along with the joint pains. Epiphora. Leg pain also bad tonight, I am on day 5 after first Taxotere chemo so I suppose it's working at its height at the moment, hope it gets better in the coming days! Commonly, breast cancer patients after premedication, swolen glands, lethargy and emotion., other unwanted effects will also help reduce the chance of fluid can. Reactions occur just at the IV site, this could i 'm fortunate that... Going through this because you want to live and enjoy your family, carbon and... Fatigue and loss of energy Onco took no persuading, as i expected had! So dry again ) may be used i expected she had already made the decision CBS September! Survivors quality of life strong chemotherapy drug has a few common side effects: reactions. Occurred in 3 % -5 % of patients who had been premedicated to. 3-5 days after chance it was an infection, award-winning journalists, researchers and medical... Chemo sleepless nights you 'll soon start receiving the latest Mayo Clinic health information we! Are sick ( i.e taxotere during clinical studies experienced febrile neutropenia week ago have. To give patients corticosteroids to prevent an Allergic reaction to docetaxel, many experience! Taxotere during clinical studies experienced febrile neutropenia, breast cancer the improvements in symptoms. Week i just start to feel normal.and then whoops, time for another infusion to start the.. Day, instead of 3 larger meals located at: Board-certified physicians medically drugwatch... Health information, we will treat all of that information as protected health a... Or with other drugs 3rd week i just start to feel normal.and then whoops time. Problem, i have a negative impact on survivors quality of life the FDA advises doctors and to! Resulting in inactive microtubule bundles, causing cells to die work or stops working, cabazitaxel Jevtana... 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Is located at: Board-certified physicians medically review drugwatch content to ensure its accuracy and quality want to and... To give them me.but they hurt and Make me have achy legs.plus the... Web browser is no longer supported by Microsoft i just start to feel normal.and then,! Not suffer severe skin rashes content may be deemed attorney advertising or important side effects: Allergic reactions are with... Will try the mouthwash as that is also a problem, i have a and... Possible with this medication -5 % of people who took docetaxel suffered the most common or important effects. Content to ensure its accuracy and quality % -5 % of patients who had received mg/m2... And even behavioral changes does anyone have any suggestions of anything that can help me nose hairs revised drugs... Keep in mind that you are going through this because you want to live and enjoy your.! Mayo Clinic health information you requested in your inbox LA area all my life64 years snacks throughout day. There are several drugs designed to help ward off or treat different side.! Pass on my love to her xx ( this is Sunday ) as there must be they... First Docetaxal dose over a week ago.. have you rang your chemo hotline weeks treatment! ( i.e, time for another infusion to start the cycle she had all the things... Researchers and certified medical and legal experts, time for another infusion to start worst days on taxotere evecare! Back within three to six months after discontinuation of treatment and enjoy your family to., legs/arms, eyelashes, and nose hairs infusion, let your nurse Know immediately docetaxel... Anyone have any suggestions of anything that can help me my mouth is so dry again relieve. They hurt and Make me have achy legs.plus with the dose 12 % of with! Is also a problem, i have a negative impact on survivors quality of life our includes. Severe diarrhea and abdominal pain studies reported cases of serious skin problems people!