Sandhu, D. K., Warraich, M. K., and Singh, S. Sensitivity of yeasts isolated from cases of vaginitis to aqueous extracts of garlic. Jpn.J Cancer Res 1999;90(6):614-621. J Nutr. Information from this source is evidence-based and objective, and without commercial influence. Pharmaceutical Biology (Netherlands) 2002;40:548-551. 2-21-2003;72(14):1583-1594. Atherosclerosis 1981;39:447-52. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. 1-15-1993;137(2):155-165. Kojuri, J., Vosoughi, A. R., and Akrami, M. Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients. Kim, Hanseul et al. Relationship between consumption of raw garlic and handgrip strength in a large-scale adult population. Acta Diabetol. 2006;76(2):173-179. Nutrition Research 1987;7:139-149. Int.J Dermatol. View abstract. View abstract. Garlic has been used safely for up to 7 years. Morris J, Burke V, Mori TA, et al. Eur J Clin Pharmacol 1993;45:333-6. View abstract. View abstract. View abstract. 10-3-2003;73(20):2543-2556. View abstract. J Nutr 2001;131:1471-8. Marsh, C. L., Torrey, R. R., Woolley, J. L., Barker, G. R., and Lau, B. H. Superiority of intravesical immunotherapy with Corynebacterium parvum and Allium sativum in control of murine bladder cancer. View abstract. View abstract. It may lead to abdominal pain, bloating, and gas in some people. WebWhat is the side effects of garlic? View abstract. Ledezma E, Marcano K, Jorquera A. Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine. 131,3s (2001): 1109S-13S. Nikolic, V., Stankovic, M., Nikolic, Lj, and Cvetkovic, D. Mechanism and kinetics of synthesis of allicin. Atherosclerosis 1999;143:399-404. Also known as blood thinners. All rights reserved. Its health action comes from the enzymes and unique compounds that it contains. View abstract. Tilli, C. M., Stavast-Kooy, A. J., Vuerstaek, J. D., Thissen, M. R., Krekels, G. A., Ramaekers, F. C., and Neumann, H. A. View abstract. Ledezma E, DeSousa L, Jorquera A, et al. Neuroscience 2003;122(4):885-895. Treudler R, Reuter A, Engin AM, Simon JC. Forsch.Komplementmed. Clin.Nutr. Horie T, Awazu S, Itakura Y, Fuwa T. Alleviation by garlic of antitumor drug-induced damage to the intestine. Because garlic can make blood less likely to clot, you should stop eating it 7 to 10 days before any surgery you have planned. Senol, M, and P Fireman. View abstract. Garlic has been used safely for up to 7 years. It can cause side effects such as bad breath, heartburn, gas, and diarrhea. These side effects are often worse with raw garlic. Garlic might also increase the risk of bleeding and cause allergic reactions in some people. Hussain, S. P., Jannu, L. N., and Rao, A. R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. Aktuelle Dermatol 1996;22:278-279. Eguchi, A., Murakami, A., and Ohigashi, H. Novel bioassay system for evaluating anti-oxidative activities of food items: use of basolateral media from differentiated Caco-2 cells. View abstract. Systemic contact dermatitis from diallyl disulfide. 2016;32(1):33-40. Lachmann, G., Lorenz, D., Radeck, W., and Steiper, M. [The pharmacokinetics of the S35 labeled labeled garlic constituents alliin, allicin and vinyldithiine]. A., Krzhivitskii, P. I., Semiglazov, V. F., Aleksandrov, V. A., Sobenin, N. A., and Orekhov, A. N. [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease]. View abstract. Excess garlic intake can cause dizziness (16). You WC, Zhang L, Gail MH, et al. View abstract. View abstract. Am J Gastroenterol. Antimicrob.Agents Chemother. Microbes Infect 1999;1:125-9. JAMA 1998;279:1900-2. 2010;9:119. BMC Cardiovasc Disord 2008;8:13. Salem, S., Salahi, M., Mohseni, M., Ahmadi, H., Mehrsai, A., Jahani, Y., and Pourmand, G. Major dietary factors and prostate cancer risk: a prospective multicenter case-control study. View abstract. Emerg.Med.J. Li WQ, Zhang JY, Ma JL, et al. Nishino, H., Iwashima, A., Itakura, Y., Matsuura, H., and Fuwa, T. Antitumor-promoting activity of garlic extracts. J Nutr. View abstract. Reuter HD and Sendl A. Allium sativum and Allium ursinum: chemistry, pharmacology and medicinal applications. Sangouni AA, Mohammad Hosseini Azar MR, Alizadeh M. Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease: a double-blind randomised controlled clinical trial. Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. Omurtag, G. Z., Guranlioglu, F. D., Sehirli, O., Arbak, S., Uslu, B., Gedik, N., and Sener, G. Protective effect of aqueous garlic extract against naphthalene-induced oxidative stress in mice. Consumption of aqueous garlic extract leads to significant improvement in patients with benign prostate hyperplasia and prostate cancer . View abstract. 2001;10(2):137-165. Ide N, Lau BH. Have you ever thought, garlic can cause serious health problems too? Thromb.Res 5-1-1986;42(3):303-311. Rahmani M, Tabari AK, Niaki MRK, and et al. Similarly, a Chinese study of several hundred lung cancer patients found that regular consumption of raw garlic was associated with a lower risk of lung cancer. Hence, it must not be taken along with blood-thinning medications like warfarin (13). Fernandez-Vozmediano JM, Armario-Hita JC, Manrique-Plaza A. Allergic contact dermatitis from diallyl disulfide. Witte JS, Longnecker MP, Bird CL, et al. Consuming milk alongside eating garlic may help reduce the malodor. There is, however, a downside to every coin, and excessive garlic consumption can be detrimental to health. Spontaneous spinal epidural hematoma with associated platelet dysfunction from excessive garlic ingestion: a case report. Levi, F., Franceschi, S., Negri, E., and La Vecchia, C. Dietary factors and the risk of endometrial cancer. View abstract. Garlic might lower blood pressure. Wang Y, Wu Y, Fu P, et al. J Nutr. View abstract. View abstract. Garlic ingestion by pregnant women alters the odor of amniotic fluid. View abstract. View abstract. Eur.J Obstet.Gynecol.Reprod.Biol. WebWhat is the side effects of garlic? However, it is typically recommended to only have 1-2 raw garlic cloves in a day.. View abstract. Anon. Urol.Int. Garlic is widely recognized for its ability to fight bacteria, viruses, fungi, and even parasites. View abstract. One randomized double-blind trial indicated that aged garlic extract, unlike fresh garlic or other garlic supplements, does not increase the risk of bleeding in patients taking warfarin. Ziaei S, Hantoshzadeh S, Rezasoltani P, Lamyian M. The effect of garlic tablet on plasma lipids and platelet aggregation in nulliparous pregnants at high risk of preeclampsia. Carcinogenesis 1995;16:2649-52. J Food Sci 2009;74(7):R84-R91. 2008;15(6):334-338. Garlic might decrease how quickly the liver breaks down tacrolimus. McNulty, C. A., Wilson, M. P., Havinga, W., Johnston, B., O'Gara, E. A., and Maslin, D. J. View abstract. 2004;50(4):467-472. Analysis of Garlic Effects on Human Health in the World. View abstract. Nutr.Cancer 2002;42(2):241-247. 2020;124(4):450-456. Senapati SK, Dey S, Dwivedi SK, Swarup D. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. AAPS Ann Mtg & Expo Indianapolis, IN: 2000; Oct 29 - Nov 2:presentation #3460. Pediatrics 1991;88:737-44. That way, you can get the maximum benefit of allicin, the compound in garlic responsible for its beneficial effects. Phytother.Res. Int J Cancer 4-1-1992;50(6):876-880. View abstract. Bradley R, Endres J, Hockenberry D, and et al. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2022;43(4):152-62. Zhang, Z. D., Li, Y., and Jiao, Z. K. [Effect of local application of allicinvia gastroscopy on cell proliferation and apoptosis of progressive gastric carcinoma]. Garty BZ. Headache 2014;54(2):378-82. Prostaglandins Leukot Essent Fatty Acids 1998;58:257-63.. View abstract. Gao, C. M., Takezaki, T., Ding, J. H., Li, M. S., and Tajima, K. Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China. Markowitz JS, Devane CL, Chavin KD, et al. View abstract. Eating too much garlic can cause bad breath, also known as halitosis, especially when eaten raw. Gaddoni G, Selvi M, Resta F, and et al. View abstract. Science 1997;278(5338):581. Dixit, V. P. and Joshi, S. Effects of chronic administration of garlic (Allium sativum Linn) on testicular function. View abstract. View abstract. Mennella JA, Beauchamp GK. View abstract. Arch.Toxicol 1996;70(10):635-639. Too much garlic can upset your digestive system, and lead to stomach issues. Garlic can cause digestion problems if had in large quantities. Gamboa-Leon, M. R., Aranda-Gonzalez, I., Mut-Martin, M., Garcia-Miss, M. R., and Dumonteil, E. In vivo and in vitro control of Leishmania mexicana due to garlic-induced NO production. 2003;15(3):120-129. Is It (Finally) Time to Stop Calling COVID a Pandemic? Lachter, J., Babich, J. P., Brookman, J. C., and Factor, A. Y. Garlic: a way out of work. Anticancer Drugs 1998;9(3):291-294. BMJ Case Rep 2014. Jain, R. C. Effect of garlic on serum lipids, coagulability and fibrinolytic activity of blood. 1996;24(3):811-814. Excessive intake of garlic can cause low blood pressure. 10 harmful effects of garlic that you should know 01 /11 Side-effects of eating too much garlic!. Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. Campos, R., Amato, Neto, V, Castanho, R. E., Moreira, A. Helicobacter pylori infection, garlic intake and precancerous lesions in a Chinese population at low risk of gastric cancer. Effect of Garlic (Allium sativum) Supplementation on Premenstrual Disorders: A Randomized, Double-Blind, Placebo-Controlled Trial. View abstract. He graduated from SRM University, Chennai, and has a Professional Certificate in Food, Nutrition & Research from Wageningen University. View abstract. Mader FH. 2005;39(12):1367-1375. Toxicol.Appl.Pharmacol. Pedraza-Chaverri, J., Maldonado, P. D., Medina-Campos, O. N., Olivares-Corichi, I. M., Granados-Silvestre, M. A., Hernandez-Pando, R., and Ibarra-Rubio, M. E. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Phytother Res 2000;14(3):215-217. Nutr.Cancer 2000;38(2):245-254. Avoid garlic if you're already taking an anticoagulant, such as Coumadin (warfarin) or Heparin, because the blood-thinning action of the medication may be increased. Farrell, A. M. and Staughton, R. C. Garlic burns mimicking herpes zoster. View abstract. Summary, evidence report/technol assessment: no 20. Ashraf, R., Khan, R. A., and Ashraf, I. Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients. View abstract. Lash, J. P., Cardoso, L. R., Mesler, P. M., Walczak, D. A., and Pollak, R. The effect of garlic on hypercholesterolemia in renal transplant patients. J Urol 1987;137(2):359-362. Journal of Natural Remedies 2006;6:19-25. Gebhardt R, Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Morioka, N., Sze, L. L., Morton, D. L., and Irie, R. F. A protein fraction from aged garlic extract enhances cytotoxicity and proliferation of human lymphocytes mediated by interleukin-2 and concanavalin A. 2003;55(2):199-202. Dorant E, van den Brandt PA, Goldbohm RA. 2003;51(3):593-597. easy bruising or bleeding (nosebleeds, bleeding gums). Petry, J. J. Garlic and postoperative bleeding. Sangouni AA, Alizadeh M, Jamalzehi A, Parastouei K. Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. Qureshi AA, Din ZZ, Abuirmeileh N, et al. 2008;28(2):108-110. Jung F, Jung EM, Mrowietz C, and et al. Clin Infect Dis 2002;34:234-8. View abstract. Numagami, Y. and Ohnishi, S. T. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. Capraz, M., Dilek, M., and Akpolat, T. Garlic, hypertension and patient education. The effects of garlic preparation against human tumour cell proliferation. Adetumbi, M., Javor, G. T., and Lau, B. H. Allium sativum (garlic) inhibits lipid synthesis by Candida albicans. View abstract. View abstract. A historical perspective on garlic and cancer. Clin.Nutr. Suzuki Y, Saito J, Misa K, Fukuhara N, Fukuhara A, Munakata M. A case of black garlic-induced pneumonia as an adverse reaction. View abstract. Qureshi A, Abuirmeileh N, Din Z, and et al. A. and Abasiyanik, F. M. Does regular garlic intake affect the prevalence of Helicobacter pylori in asymptomatic subjects? Arch Intern Med 2007;167:346-53. The role of garlic in hepatopulmonary syndrome: a randomized controlled trial. View abstract. Am J Epidemiol. Many studies have found that garlic can reduce the chances that blood clots will form. Speak with a healthcare provider to find out what dose might be best for a specific condition. Efficacy of Oral Administration of Allium sativum Powder "Garlic Extract" on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients. 1988;134 ( Pt 11):2917-2924. J Clin Biochem Nutr 2020;67(3):297-301. JAMA 2001;285:41,42. Koscielny J, Klussendorf D, Latza R, et al. According to Consumer Reports, black garlic is aged under high heat and humidity for 10 days. Arzneimittelforschung. Phytother.Res. A., and Orekhov, A. N. [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]. It's a good idea to look for supplements that are coated (enteric coating) so they will dissolve in the intestine and not in the stomach. The effects of oral garlic on vaginal candida colony counts: a randomised placebo controlled double-blind trial. Oberle M, Wachs T, Brisson P. Garlic burn to the face. [Epub ahead of print] View abstract. View abstract. Ashraf, R., Aamir, K., Shaikh, A. R., and Ahmed, T. Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus. In fact, eating too much garlic can lead to adverse effects. Candidiasis (vulvovaginal).BMJ clinical evidencevol. Effect of supplementation with garlic oil on activity of Th1 and Th2 lymphocytes from rats. Gao YT, McLaughlin JK, and Gridley G. Risk factors for esophageal cancer in Shanghai, China. 67,1 (2013): 64-70. Ledezma E, Lopez JC, Marin P, et al. Lipids 1996;31:1269-76. Filobbos, G., Chapman, T., and Gesakis, K. Iatrogenic burns from garlic. View abstract. Wohlrab, J., Wohlrab, D., and Marsch, W. C. Acute effect of a dried ethanol-water extract of garlic on the microhaemovascular system of the skin. 2016;19(2):308-17. View abstract. Gerontology 2008;54(3):173-176. Alder, R., Lookinland, S., Berry, J. Pediatr Res 1993;34:805-8.

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